Bioscientifica Proceedings

The corpus luteum is a transient gland, which is only functional for 17–18 days in the cyclic cow or for up to 200 days in the pregnant cow. Regression of the corpus luteum is essential for normal cyclicity as it allows the development of a new ovulatory follicle, whereas prevention of luteolysis is necessary for the maintenance of pregnancy. Evidence acquired over the past three decades indicated that PGF2α is the luteolytic hormone in ruminants. Neverthe...